Baseline Study: Breathing Gas Analysis SARS-CoV-2 Infections 

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Detecting Coronaviruses in exhaled breath

In medical engineering there are several promising approaches based on the measurement of chemical and biological substances in exhaled breath, for example anesthetics. The technology enables anesthetists to continuously monitor the concentration of drugs in the patient’s body in a noninvasive and therefore comfortable way. B. Braun’s technology, among others, is already in use within anesthesia departments. This has led several teams world-wide including B. Braun to consider whether coronaviruses or related reactions of the body can be detected with this or any related technology, too.

COVID-19 research –clinical trial

Can a SARS-COV 2 infection be diagnosed through exhaled breath? That is the central question of B. Braun’s clinical trial, running since December 2020. Therefore, the exhaled breath of people, having been found to have the Coronavirus SARS-COV 2, is compared to the exhaled breath of non-infected test persons. To get a meaningful result, each group consists of 200 persons. 

The test: fast, easy, effective

To test the exhaled breath, participants of the clinical trial just need to breathe into the tester for one minute. The results are compared with the results of the PCR-Test, and then, the anonymized data are being evaluated at the Center of Competence Breath Analysis of B. Braun Melsungen AG in cooperation with the Department of BioEngineering at the Technical University of Munich.