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Reducing Underdosing


a cause of medication errors

underdosage graphic

In small volume infusions up to 32.2% of active agent remain in IV line3

(last access June 2021)


[1] Toh MR et al, Prev Med Reports 2014;1:43-473. Plagge H et al, EJHPScience 2010;16:31-37

[2] Hughes RG et al, Evidence-based Handbook for Nurses 2008; US Dept of Health and Human Services

[3] Plagge H et al, EJHPSCience 2010;16:31-37


[5]. Cousins D et al, Clinical Pharmacist 2018;10(12):356-357

[6] Patient Safety Observer, 2007

[7] Cooper DM et al, Bri J Nurs 2018;27:2-6

[8] Gregerson BG et al, Proc Bayl Univ Med Cent 2018;31(2):168-170

[9] Chan YK et al, CMBES Proc., vol 36, no1, May 2013

[10] Letter by Cousins D in the Clinical Pharmacist & Cooper et al


[12] MacLachlan L et al, Antimicrobial Stewardship – Ensuring full prescribed Dose Delivery of IV Antibiotics in OPAT, Hull University Teaching Hospitals, NHS Trust

[13] Fish and Ohlinger, 2006

[14] CDC 2015,

[15] Gurney H et al, Bri J Cancer 2002;86:1297-1302

[16] Bowman S et al, Anaesthesia 2013;68:557-561

[17] Cooper DM et al, BJON 2018;27:14(suppl_000


[19] Peyko, V., An unrecognized Problem in Optimizing Antimicrobial Therapy: Significant Residual Volume Remaining in Intravenous Tubing With Extended-Infusion Piperacillin-Tazobactam, 2021 Journal of Pharmacy Practice Vol. 0.0 1-4

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