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SeQuent® DCBs

The proven performers in coronary angioplasty

Backing up cardiologists with unparalleled clinical data and proven performance for both paclitaxel and sirolimus coated balloons.

Paclitaxel and sirolimus coated balloons

SeQuent® DCBs – The choice is yours.

B. Braun´s paclitaxel coated balloon SeQuent® Please NEO is the best investigated DCB [1] in the field of percutaneous coronary interventions (PCI). It has demonstrated its convincing performance, efficacy and safety in more than 110 published studies (including more than 35 RCTs) – with over 25,000 documented patients, conducted in more than 20 countries. 

SeQuent® Please NEO for coronary angioplasty
Studies Grafik

Clinical evidence

Publications for SeQuent® Please / NEO

The coronary DCB has been investigated in more than 110 studies with over 25,000 documented patients, conducted in more than 20 countries.
All clinical trials at a glance as PDF download

Study summaries SeQuent® Please / NEO

Randomized controlled trials

Not randomized controlled trials & observational studies

Clinical evidence SeQuent® SCB

Preclinical work and randomized controlled trials

Treatment methodology

According to Consensus Group recommendations [6], [7]

Lesion preparation

Acceptable angiographic result

  • No dissection or only Type A or B
    No flow limiting dissection
  • TIMI III / FFR > 0.8
  • Residual stenosis ≤ 30 %

Unacceptable angiographic result

  • Dissection Type C-F
    Flow limiting dissection
  • TIMI < III / FFR < 0.8
  • Residual stenosis > 30 %

Lesion therapy

DCB-only with with SeQuent® Please NEO or SeQuent® SCB

  • De-Novo
  • ISR


  • DES implantation with Coroflex® ISAR NEO

Related products

Related documents

SeQuent® Please NEO

Clinically proven drug coated balloon catheter

pdf, 1.2 MB

download Download

SeQuent® SCB

Sirolimus coated balloon catheter for PTCA

pdf, 1.7 MB

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SeQuent® Please NEO – Go Implant-Free!

Safe and effective alternative to DES in de novo lesions

pdf, 27.8 KB

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Cardiology Catalog

Your partner for coronary angioplasty

pdf, 1.8 MB

download Download

[1] All numbers referring to clinical coronary trials on PCBs, patients enrolled therein and countries in which these trials were conducted, are based on a PubMed literature search conducted with due diligence in February/March 2022. (Data on file at B. Braun)

[2] Ali RM et al J Am Coll Cardiol Intv 2019;12:558-66

[3] Scheller B et al. Circ Cardiovasc Interv. 2022 Sep;15(9):e012305.

[4] Ahmad WAW et al. JACC Cardiovasc Interv. 2022 Apr 11;15(7):770-779

[5] Clever et al. Circ Cardiovasc Interv. 2016 Apr;9(4):e003543.

[6] Kleber FX et al. Clin Res Cardiol. 2013 Nov;102(11):785-97.

[7] Jeger RV et JACC Cardiovasc Interv. 2020 Jun 22;13(12):1391-1402.


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