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Your Way to Confidence
Enter the world of SeQuent® DCB treatment with cutting-edge balloon technology and a proven leader at your side – for more drug options, more clinical data, high-quality support and the confidence you’re aiming for.
Implant-free coronary angioplasty
Drug coated balloon technology – it’s a crucial element in the future of coronary angioplasty for delivering highly effective, implant-free treatment to patients.
As a pioneer and key player in the drug coated balloon field, B. Braun is actively engaged with the interventional cardiology community worldwide – organizing forums for peer-to-peer exchange of treatment strategies, hosting lectures by leading experts and delivering hands-on practical training.
Guided by expertise
Leading experts from around the globe share their experiences with drug coated balloons. Dive deep into their DCB practices and gain unique insights, all guided by real-world experience and expert knowledge.
Clinical evidence
B. Braun has been at the forefront of DCB technology from the start – opening up and confirming best-practice options for drug coated balloons with both paclitaxel and sirolimus. B. Braun’s longterm commitment to the DCB field has established an impressive record of clinical evidence – and offers a dynamic way forward, regardless of your preferred treatment drug.
It’s the special crystalline coating of SeQuent® DCBs that makes the most of a DCB’s short period of inflation. Confirmed through large clinical data sets, the sharp-edged spike structures of the crystals ensure the drug’s persistence in the vessel wall.
Paclitaxel coated balloon
SeQuent® Please NEO
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2020 | Primary Investigator: Jeger R | Study Aim: SQP vs. DES, Vessel: RD ≤ 3 mm | (Primary) Endpoint: MACE @ 36-month follow-up | Patients: 758
Summary BASKET-SMALL 22017 | Primary Investigator: Funatsu A | Study Aim: DCB vs. POBA, Vessel: RD ≤ 2.75 mm, ≥ 2 mm | (Primary) Endpoint: TVF @ 6-month follow-up | Patients: 135
Summary PEPCAD Japan SVD2017 | Primary Investigator: Gobić D | Study Aim: DCB vs. DES, Patients: STEMI (< 12 h) | (Primary) Endpoint: MACE, LLL @ 6-month follow-up | Patients: 75
Summary AMI Feasibility Study2016 | Primary Investigator: Nishiyama N | Study Aim: DCB vs. DES | (Primary) Endpoint: TLR @ 8-month follow-up | Patients: 60
Summary Clinical Value "Stent-less" PCI2019 | Primary Investigator: Rosenberg M | Study Aim: DCB – ISR & De Novo | (Primary) Endpoint: TLR @ 9-month follow-up | Patients: 1,025
Summary DCB-only All-Comers Registry2016 | Primary Investigator: Shin E | Study Aim: DCB – De Novo, Vessel: RD ≤ 3.5 mm, ≥ 2.5 mm | (Primary) Endpoint: LLL, FFR @ 9-month follow-up, MI, TLR @ 12-month follow-up | Patients: 67
Summary FFR-Guided DCB-Angioplasty2014 | Primary Investigator: Zeymer U | Study Aim: DCB – De Novo, Vessel: RD ≤ 2.75 mm, ≥ 2.0 mm | (Primary) Endpoint: TLR @ 9-month follow-up | Patients: 447
Summary SVD Registry2023 | Primary Investigator: Shin ES | Study Aim: Investigate the impact of DCB-based treatment on PCI for multivessel CAD | (Primary) Endpoint: MACE @ 24-months (cardiac death, MI, TVR, stroke, stent thrombosis and major bleeding) | Patients: 508
Summary DCB-based PCI in Multi-Vessel-DiseaseSirolimus coated balloon
B. Braun´s sirolimus coated balloon is the first SCB backed up with published randomized clinical trials for ISR and de-novo lesions.[2], [3], [4] SeQuent® SCB offers new implant-free options for treating coronary ISR and de-novo lesions, providing excellent results in targeted drug delivery and sirolimus persistence. The combination of sirolimus and BHT (Butylated Hydroxy Toluol) creates the desired crystalline sirolimus modification to reach best results regarding sirolimus vessel wall content compared to other excipients.[5]
Sirolimus + BHT (Butylated Hydroxy Toluol): Persistence in the vessel wall
Read moreTwo RCTs for SeQuent® SCB vs. SeQuent® Please NEO with angiographic and clinical follow-ups.
Read summaryRCT for SeQuent® SCB vs. SeQuent® Please NEO with angiographic and clinical follow-ups.
Read summary
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