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Histoacryl® Flexible

Fast, Reliable Skin Closure with Histoacryl® Flexible

Histoacryl® Flexible Pack is a clinically proven tissue adhesive for minimum‑tension skin closure. This unique and versatile butyl-cyanoacrylate solution easily adapts to wounds ranging from small cuts to long incisions up to 25 cm1-3. Its microbial barrier4-5, rapid polymerization, and painless application support safe, effective wound closure and faster recovery6.Trusted worldwide, B. Braun brings quality and innovation to Skin Closure.

The advanced choice for skin closure

Two skin closure adhesive tubes with blue skin adhesive on a grey ground, behind you can see a peel off blister package of the skin adhesive.

Enhanced visibility

Histoacryl® Flexible’s distinctive blue color improves visibility during application.

Ideal for long incisions

Its formulation includes a softener that provides extra flexibility and makes it ideal for incisions up to 25 cm.1-3

Adhesive distribution

An optional applicator tip facilitates easy distribution of the adhesive over the wound.

“Easy to use for patients of any age, providing fast*, complication‑free adhesion and excellent cosmetic healing – with the wound fully healed after one month.”

Joseph Jennings Mettekatte Michael, Registered Nurse, Case: Laceration on the forehead, patient 3 years old.
*Consult the IFU to confirm the approved patient population
  • used in more than

    0

    countries around the world

  • more than

    0

    years of experience

  • for incisions up to

    0

    centimeters

Questions & Answers on Histoacryl® Flexible

Breast surgery icon

Breast Surgery10

C-Sections11

Circumcisions12

Emergency Lacerations13-15

Central Venous Port Implantation8

Facial Plastic and Reconstructive Procedures16,17

Panniculectomy and abdominoplasty18

Pediatric Nail Bed Injuries19

Perineal Skin Tear Repair Following Vaginal Birth6

Total Hip Arthroplasty20

“Single application. Easy to use. Good cosmetic results.”

Theona Stone, Nurse Practitioner, Case: Laceration, 3-year-old patient

No dressing is needed afterwards

Showering is allowed

No removal visit required;  spontaneously detaches within 4-8 days7

Histoacryl® Flexible Pack Portfolio

Get in touch with our experts

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References

 
  1. Report ECT / Dr. Gabriel Siedle / Test of the flexibility of Histoacryl® and Histoacryl® Flexible, November 2012 
  2. Frey-Tox Report / Lab.- Nr. 03145 / Flexible Gewebekleber
  3. RDR/DID/CHM/DCE/16106 – Validation of Histoacryl® Flexible_in vivo study
  4. Internal Report_MDT medical device testing GmbH report / Project 12m020 / Determination of Microbiological Barrier Properties of Two Topical Skin Adhesives
  5. MDT microbial device testing GmbH report / Project 13m155 / Determination of Microbiological Barrier Properties of Two Topical 
  6. Dasrilsyah RA, Kalok A, Ng BK, Ali A, Teik Chew K, Lim PS. Perineal skin tear repair following vaginal birth; skin adhesive versus conventional suture - a randomised controlled trial. J Obstet Gynaecol. 2021;41(2):242-247.
  7. Histoacryl® Flexible Instructions for Use
  8. Witting S, Ingwersen M, Lehmann T, Aschenbach R, Eckardt N, Jürgen Zanow, et al. Wound Closure After Port Implantation-A Randomized Controlled Trial Comparing Tissue Adhesive and Intracutaneous Suturing. Dtsch Arztebl Int. 2021;118(44):749-55.
  9. RDR/DID/CHM/SLE/20053 – Real Time Stability Study on Histoacryl Flexible – 25 ºC – 60% 
  10. Sun T, Liu S, Sun G. Application of Histoacryl Tissue Glue in Breast Surgery. IOP Conf Ser Mater Sci Eng 2019;562(1):012144.
  11. Kwon JY, Yun HG, Park IY. n-Butyl-2-cyanoacrylate tissue adhesive (Histoacryl) vs. Subcuticular sutures for skin closure of Pfannenstiel incisions following cesarean delivery. PLoS One. 2018;13(9):e0202074.
  12. Huang C, Wan, T, Weng L, Chen H. Useful Tips and Tricks for Secure Circumcision. Urological Science. 2019;30(3):p 136-139
  13. Farion KJ, Russell KF, Osmond MH, Hartling L, Klassen TP, Durec T, et al.Tissue adhesives for traumatic lacerations in children and adults. Cochrane Database Syst Rev. 2002;2002(3):CD003326.
  14. Bruns TB, Simon HK, McLario DJ, Sullivan KM, Wood RJ, Anand KJ. Laceration repair using a tissue adhesive in a children’s emergency department. Pediatrics. 1996;98 (4 Pt 1):673-675.
  15. Barnett P, Jarman FC, Goodge J, Silk G, Aickin R. Randomized trial of histoacryl blue tissue adhesive glue versus suturing in the repair of paediatric lacerations. J Paediatr Child Health. 1998; 34(6):548-50.
  16. Veloudios A, Kratky V, Heathcote JG, Lee M, Hurwitz JJ, Kazdan MS. Cyanoacrylate tissue adhesive in blepharoplasty. Ophthalmic Plast Reconstr Surg. 1996;12(2):809-97.
  17. Ellis DA, Shaikh A. The ideal tissue adhesive in facial plastic and reconstructive surgery. J Otolaryngol. 1990;19(1):68-72.
  18. Koonce SL, Eck DL, Shaddix KK, Perdikis G. A prospective randomized controlled trialcomparing N-butyl-2 cyanoacrylate (Histoacryl), octyl cyanoacrylate (Dermabond), andsubcuticular suture for closure of surgical incisions. Ann Plast Surg. 2015;74(1):107-10.
  19. Edwards S, Parkinson L. Is Fixing Pediatric Nail Bed Injuries With Medical Adhesives as Effective as Suturing?: A Review of the Literature. Pediatr Emerg Care. 2019;35(1):75-77
  20. Kong X, Yang M, Cao Z, Chen J, Chai W, Wang Y. Tissue adhesive for wound closure inenhanced-recovery total hip arthroplasty: a prospective, randomized and controlled study.BMC Musculoskelet Disord. 2020;21(1):178.