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Wound bed preparation
Biofilm is very likely present in non-healing chronic human wounds. Awareness of this presence is as important as the knowledge of distinct phenotype differences, especially in terms of the challenge to remove and eradicate biofilm from a wound.
 Malone M, Bjarnsholt T, McBain AJ, James GA, Stoodley P, Leaper D, Tachi M, Schultz G, Swanson T, Wolcott RD. The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data. J Wound Care. 2017 Jan 2;26(1):20-25. doi: 10.12968/jowc.2017.26.1.20. PMID: 28103163.
 Falanga V. Classifications for wound bed preparation and stimulation of chronic wounds. Wound Repair Regen. 2000 Sep-Oct;8(5):347-52. PMID: 11115147.