Wound bed preparation
against biofilm formation

Biofilm - a major issue in wound healing

The presence of biofilm is reportedly present in 60-100% of non-healing wounds (WUWHS Biofilm Position Paper, 2016). While the role that biofilm plays in the chronicity of wounds is still not fully investigated, it is becoming widely accepted that hard-to-heal wounds contain biofilm - and somehow its presence delays or prevents healing. 

Therefore the management of biofilm in chronic wounds is rapidly becoming a primary object of wound care. 

Only a clean wound can heal

The concept of  ”Wound bed preparation“ was first described by Falanga et al (2000) and can be defined as the global wound management procedure to accelerate endogenous healing and enhance the effectiveness of advanced wound care products. The ultimate aim is to ensure healthy granulation tissue formation resulting in complete wound closure.

Correct Chronic "Wound bed preparation" is achieved by:

• Reducing bacterial bioburden e.g. biofilm in the wound bed
• Removing necrotic tissue and slough
• Controling exudates
• Managing cellular dysfunctions and biochemical imbalances

With Prontosan^®  we provide a leading concept for wound bed preparation based on an unique combination of Polihexanide and Betaine. Several clinical studies prove faster wound closure, less complications and better quality of life. Prontosan^® helps manage infection prevention, cleansing/debridement as well as wound bed moistening. Prontosan^®  is your partner in preventing and treating the formation of biofilms.

How do microfibers work?

Microfibers are able to attach themselves to even the smallest, most microscopic particles—ones that normal monofilament fibers (positively giant in comparison) crudely brush past. If forces were visible, you‘d be able to see that there are adhesive forces between microfibers and the particles. There are millions of microfibers in a pad, so the overall sticking effect is magnified dramatically. That‘s why cell residues (debris), exudate and slough can be «hoovered up» by microfiber cloths. 

In this '5minutes, 5 questions' series of talking heads, Professor Keith Harding, Professor Marco Romanelli and Dr Bjorn Behr answer key questions about the concept of wound bed preparation. 

^{*Seipp HM et al. Efficacy of various wound rinsing solutions against biofilms. ZfW 2005; 4(5):160-163 / Perez R et al. Effect of different wound rinsing solutions on MRSA biofilm in a porcine model. WoundM 2010; 4(2):44-48}

^{1) Attinger, Christopher and Randy Wolcott. “Clinically Addressing Biofilm In Chronic Wounds”. Advances in Wound Care 1.3 (2012): 127-132. Web.}

^{2) Bjarnsholt, T et al. “Biofilm Management”. 2016. Lecture.}

^{3) International Wound Infection Institute (IWII): Wound infection in clinical practice. Wounds International;2016.}

^{4) Bradbury, S and J Fletcher. “Prontosan Made Easy”. Wounds International 2.2 (2016): 1-6. Web. 23 Sept. 2016.}

^{5) Kaehn, K Polihexanide: A Safe and Highly Effective Biocide, Skin Pharmacol Physiol 2010;23(suppl1);7-16}